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AKA-384
Tedizolid phosphate
Cat. No.
AKA-384
CAS No.
856867-55-5
MF
C17H16FN6O6P
MW
450.32
Tedizolid phosphate is an oxazolidinone antibacterial prodrug featuring an oxazolidinone ring, a fluorinated aryl group, and a tetrazole heterocycle, with inhibitory activity against monoamine oxidase A (MAO-A) and B (MAO-B).
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Technical Data
Description
Documents
Storage and Shipping
References
Product Name
Tedizolid phosphate
CAS No.
856867-55-5
MF
C17H16FN6O6P
MW
450.32
Specification
98.0%~102.0%
Description
Tedizolid phosphate is an oxazolidinone antibacterial prodrug featuring an oxazolidinone ring, a fluorinated aryl group, and a tetrazole heterocycle, with inhibitory activity against monoamine oxidase A (MAO-A) and B (MAO-B). Packing: 1kg/bag，5kg/bag，25kg/bag Availability: In stock API Current Development Status: A3---Process Development / Scale-Up Reference: Aktin major API development processes: A1.Feasibility / Route Development A2.Laboratory Process Development A3.Process Development / Scale-Up A4.GMP Clinical Development A5.Commercial GMP Supply
Documents
Certificate of Analysis (COA), API specification sheet, Safety Data Sheet (SDS/MSDS), evidence of GMP compliance, Stability data / Stability summary, etc.
Storage and Shipping
Store in a cool and dry place, avoid strong light and high temperature.
References
[1].Im WB, Choi SH, Park JY, Choi SH, Finn J, Yoon SH. Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agent. Eur J Med Chem. 2011;46(4):1027-1039. doi:10.1016/j.ejmech.2011.01.014
[2].Lei Y, Jin B, Ma C, Zhang T, Li T. Identification of forced degradation products of tedizolid phosphate by liquid chromatography/electrospray ionization tandem mass spectrometry. J Pharm Biomed Anal. 2017;139:221-231. doi:10.1016/j.jpba.2017.03.006
[3].Prokocimer P, Bien P, DeAnda C, Pillar CM, Bartizal K. In vitro activity and microbiological efficacy of tedizolid (TR-700) against Gram-positive clinical isolates from a phase 2 study of oral tedizolid phosphate (TR-701) in patients with complicated skin and skin structure infections. Antimicrob Agents Chemother. 2012;56(9):4608-4613. doi:10.1128/AAC.00458-12
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